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Nonredox thiolation in tRNA occurring via sulfur activation by a [4Fe-4S] cluster
Sulfur is present in several nucleosides within tRNAs. In particular, thiolation of the universally conserved methyl-uridine at position 54 stabilizes tRNAs from thermophilic bacteria and hyperthermophilic archaea and is required for growth at high temperature. The simple nonredox substitution of th...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5514717/ https://ncbi.nlm.nih.gov/pubmed/28655838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700902114 |
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