Multiparity improves outcomes after cerebral ischemia in female mice despite features of increased metabovascular risk

Females show a varying degree of ischemic sensitivity throughout their lifespan, which is not fully explained by hormonal or genetic factors. Epidemiological data suggest that sex-specific life experiences such as pregnancy increase stroke risk. This work evaluated the role of parity on stroke outco...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Ritzel, Rodney M., Patel, Anita R., Spychala, Monica, Verma, Rajkumar, Crapser, Joshua, Koellhoffer, Edward C., Schrecengost, Anna, Jellison, Evan R., Zhu, Liang, Venna, Venugopal Reddy, McCullough, Louise D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514696/
https://ncbi.nlm.nih.gov/pubmed/28645895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1607002114
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