Age-associated resident memory CD8 T cells in the CNS are primed to potentiate inflammation after ischemic brain injury

Aging is associated with an increase in basal inflammation in the central nervous system (CNS) and an overall decline in cognitive function and poorer recovery following injury. Growing evidence suggests that leukocyte recruitment to the CNS is also increased with normal aging, but to date, no syste...

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Udgivet i:J Immunol
Main Authors: Ritzel, Rodney M., Crapser, Joshua, Patel, Anita R., Verma, Rajkumer, Grenier, Jeremy M., Chauhan, Anjali, Jellison, Evan R., McCullough, Louise D.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868658/
https://ncbi.nlm.nih.gov/pubmed/26962232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502021
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