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Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na(+),K(+)-ATPase Blocks HIV-1 Infection

Besides its essential role in the activation of HIV-1 gene expression, the viral Tat protein has the unusual property of trafficking in and out of cells. In contrast to Tat internalization, the mechanism involved in extracellular Tat release has so far remained elusive. Here we show that Tat secreti...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Agostini, Silvia, Ali, Hashim, Vardabasso, Chiara, Fittipaldi, Antonio, Tasciotti, Ennio, Cereseto, Anna, Bugatti, Antonella, Rusnati, Marco, Lusic, Marina, Giacca, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514404/
https://ncbi.nlm.nih.gov/pubmed/28645727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.06.011
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