Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na(+),K(+)-ATPase Blocks HIV-1 Infection

Besides its essential role in the activation of HIV-1 gene expression, the viral Tat protein has the unusual property of trafficking in and out of cells. In contrast to Tat internalization, the mechanism involved in extracellular Tat release has so far remained elusive. Here we show that Tat secreti...

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Vydáno v:EBioMedicine
Hlavní autoři: Agostini, Silvia, Ali, Hashim, Vardabasso, Chiara, Fittipaldi, Antonio, Tasciotti, Ennio, Cereseto, Anna, Bugatti, Antonella, Rusnati, Marco, Lusic, Marina, Giacca, Mauro
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514404/
https://ncbi.nlm.nih.gov/pubmed/28645727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.06.011
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