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Activin signaling is an essential component of the TGF-β induced pro-metastatic phenotype in colorectal cancer

Advanced colorectal cancer (CRC) remains a critical health care challenge worldwide. Various TGF-β superfamily members are important in colorectal cancer metastasis, but their signaling effects and predictive value have only been assessed in isolation. Here, we examine cross-regulation and combined...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Staudacher, Jonas J., Bauer, Jessica, Jana, Arundhati, Tian, Jun, Carroll, Timothy, Mancinelli, Georgina, Özden, Özkan, Krett, Nancy, Guzman, Grace, Kerr, David, Grippo, Paul, Jung, Barbara
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514149/
https://ncbi.nlm.nih.gov/pubmed/28717230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05907-8
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