Stability of the PHF10 subunit of PBAF signature module is regulated by phosphorylation: role of β-TrCP

The PBAF chromatin-remodeling complexes are multi-protein machines, regulating expression of genes involved in proliferation and differentiation. PHF10 is a subunit of the PBAF essential for its association with chromatin. Mammalian PHF10 is expressed as four ubiquitous isoforms, which are alternati...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tatarskiy, Victor V., Simonov, Yuriy P., Shcherbinin, Dmitrii S., Brechalov, Alexander V., Georgieva, Sofia G., Soshnikova, Nataliya V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514133/
https://ncbi.nlm.nih.gov/pubmed/28717195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05944-3
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