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Quantifying three-dimensional rodent retina vascular development using optical tissue clearing and light-sheet microscopy

Retinal vasculature develops in a highly orchestrated three-dimensional (3-D) sequence. The stages of retinal vascularization are highly susceptible to oxygen perturbations. We demonstrate that optical tissue clearing of intact rat retinas and light-sheet microscopy provides rapid 3-D characterizati...

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Bibliografiska uppgifter
I publikationen:J Biomed Opt
Huvudupphovsmän: Singh, Jasmine N., Nowlin, Taylor M., Seedorf, Gregory J., Abman, Steven H., Shepherd, Douglas P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society of Photo-Optical Instrumentation Engineers 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514054/
https://ncbi.nlm.nih.gov/pubmed/28717817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.22.7.076011
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