Development of a sandwich enzyme-linked immunosorbent assay for dTMP-GH fusion protein by rational immunogen selection

dTMP-GH is a chimeric protein containing a tandem dimer of thrombopoietin mimetic peptide (dTMP) fused to human growth hormone (hGH) prepared previously by our team. It shows significant bioactivity in promoting thrombocytopoiesis, but detection of intact dTMP-GH in plasma is still a challenge due t...

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Bibliografiske detaljer
Udgivet i:AMB Express
Main Authors: Wang, Song, Shen, Mingqiang, Chen, Shilei, Wang, Cheng, Chen, Fang, Chen, Mo, Zhao, Gaomei, Ran, Xinze, Cheng, Tianmin, Su, Yongping, Xu, Yang, Wang, Junping
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2017
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514005/
https://ncbi.nlm.nih.gov/pubmed/28724261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-017-0454-6
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