ETV1-positive cells give rise to BRAF(V600E) mutant gastrointestinal stromal tumors

Gastrointestinal Stromal Tumor (GIST) is the most common subtype of sarcoma. Despite clinical advances in the treatment of KIT/PDGFRA-mutant GIST, similar progress against KIT/PDGFRA-wild type GIST, including mutant BRAF-driven tumors, have been limited by a lack of model systems. ETV1 is a master r...

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Pubblicato in:Cancer Res
Autori principali: Ran, Leili, Murphy, Devan, Sher, Jessica, Cao, Zhen, Wang, Shangqian, Walczak, Edward, Guan, Youxin, Xie, Yuanyuan, Shukla, Shipra, Zhan, Yu, Antonescu, Cristina R., Chen, Yu, Chi, Ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513719/
https://ncbi.nlm.nih.gov/pubmed/28539323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-3510
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