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Cofactor engineering improved CALB production in Pichia pastoris through heterologous expression of NADH oxidase and adenylate kinase

The cofactor engineering strategy can relieve the metabolic stress induced by expression of recombinant protein in cellular metabolism related to cofactor and energy reactions. To study the effect of cofactor regeneration on recombinant protein expression, NADH oxidase (noxE) was engineered in P. pa...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Jayachandran, Charumathi, Palanisamy Athiyaman, Balakumaran, Sankaranarayanan, Meenakshisundaram
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513558/
https://ncbi.nlm.nih.gov/pubmed/28715469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181370
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