Cofactor engineering improved CALB production in Pichia pastoris through heterologous expression of NADH oxidase and adenylate kinase

The cofactor engineering strategy can relieve the metabolic stress induced by expression of recombinant protein in cellular metabolism related to cofactor and energy reactions. To study the effect of cofactor regeneration on recombinant protein expression, NADH oxidase (noxE) was engineered in P. pa...

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Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Jayachandran, Charumathi, Palanisamy Athiyaman, Balakumaran, Sankaranarayanan, Meenakshisundaram
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513558/
https://ncbi.nlm.nih.gov/pubmed/28715469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181370
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