Whole Genome Sequencing Predicts Novel Human Disease Models in Rhesus Macaques

Rhesus macaques are an important pre-clinical model of human disease. To advance our understanding of genomic variation that may influence disease, we surveyed genome-wide variation in 21 rhesus macaques. We employed best-practice variant calling, validated with Mendelian inheritance. Next, we used...

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Vydáno v:Genomics
Hlavní autoři: Bimber, Benjamin N., Ramakrishnan, Ranjani, Cervera-Juanes, Rita, Madhira, Ravi, Peterson, Samuel M, Norgren, Robert B., Ferguson, Betsy
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513488/
https://ncbi.nlm.nih.gov/pubmed/28438488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2017.04.001
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