Whole Genome Sequencing Predicts Novel Human Disease Models in Rhesus Macaques

Rhesus macaques are an important pre-clinical model of human disease. To advance our understanding of genomic variation that may influence disease, we surveyed genome-wide variation in 21 rhesus macaques. We employed best-practice variant calling, validated with Mendelian inheritance. Next, we used...

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發表在:Genomics
Main Authors: Bimber, Benjamin N., Ramakrishnan, Ranjani, Cervera-Juanes, Rita, Madhira, Ravi, Peterson, Samuel M, Norgren, Robert B., Ferguson, Betsy
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513488/
https://ncbi.nlm.nih.gov/pubmed/28438488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2017.04.001
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