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SLC46 family transporters facilitate cytosolic innate immune recognition of monomeric peptidoglycans

Tracheal Cytotoxin (TCT), a monomer of DAP-type peptidoglycan (PGN) from B. pertussis, causes cytopathology in the respiratory epithelia in mammals and robustly triggers the Drosophila Imd pathway. PGRP-LE, a cytosolic innate immune sensor in Drosophila, directly recognizes TCT and triggers the Imd...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Paik, Donggi, Monahan, Amanda, Caffrey, Daniel R., Elling, Roland, Goldman, William E., Silverman, Neal
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513181/
https://ncbi.nlm.nih.gov/pubmed/28539433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600409
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