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SLC46 family transporters facilitate cytosolic innate immune recognition of monomeric peptidoglycans
Tracheal Cytotoxin (TCT), a monomer of DAP-type peptidoglycan (PGN) from B. pertussis, causes cytopathology in the respiratory epithelia in mammals and robustly triggers the Drosophila Imd pathway. PGRP-LE, a cytosolic innate immune sensor in Drosophila, directly recognizes TCT and triggers the Imd...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5513181/ https://ncbi.nlm.nih.gov/pubmed/28539433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600409 |
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