Increased conversion of phosphatidylinositol to phosphatidylinositol phosphate in Dictyostelium cells expressing a mutated ras gene.

Dictyostelium discoideum cells that overexpress a ras gene with a Gly12----Thr12 mutation (Dd-ras-Thr12) have an altered phenotype. These cells were labeled with [3H]inositol and the incorporation of radioactivity into inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] was analyzed and found to be higher t...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Van der Kaay, J, Draijer, R, Van Haastert, P J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55131/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2174555/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.23.9197
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