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Uniform cAMP Stimulation of Dictyostelium Cells Induces Localized Patches of Signal Transduction and Pseudopodia

The chemoattractant cAMP induces the translocation of cytosolic PH(Crac)-GFP to the plasma membrane. PH(Crac)-GFP is a green fluorescent protein fused to a PH domain that presumably binds to phosphatydylinositol polyphosphates in the membrane. We determined the relative concentration of PH(Crac)-GFP...

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Bibliografiske detaljer
Main Authors: Postma, Marten, Roelofs, Jeroen, Goedhart, Joachim, Gadella, Theodorus W.J., Visser, Antonie J.W.G., Van Haastert, Peter J.M.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC284803/
https://ncbi.nlm.nih.gov/pubmed/14595105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-08-0566
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