Uniform cAMP Stimulation of Dictyostelium Cells Induces Localized Patches of Signal Transduction and Pseudopodia

The chemoattractant cAMP induces the translocation of cytosolic PH(Crac)-GFP to the plasma membrane. PH(Crac)-GFP is a green fluorescent protein fused to a PH domain that presumably binds to phosphatydylinositol polyphosphates in the membrane. We determined the relative concentration of PH(Crac)-GFP...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Postma, Marten, Roelofs, Jeroen, Goedhart, Joachim, Gadella, Theodorus W.J., Visser, Antonie J.W.G., Van Haastert, Peter J.M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 2003
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Articles
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC284803/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14595105/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-08-0566
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