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A rare-variant test for high-dimensional data

Genome-wide association studies have facilitated the discovery of thousands of loci for hundreds of phenotypes. However, the issue of missing heritability remains unsolved for most complex traits. Locus discovery could be enhanced with both improved power through multi-phenotype analysis (MPA) and u...

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Bibliografiske detaljer
Udgivet i:Eur J Hum Genet
Main Authors: Kaakinen, Marika, Mägi, Reedik, Fischer, Krista, Heikkinen, Jani, Järvelin, Marjo-Riitta, Morris, Andrew P, Prokopenko, Inga
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513099/
https://ncbi.nlm.nih.gov/pubmed/28537275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2017.90
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