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A rare-variant test for high-dimensional data

Genome-wide association studies have facilitated the discovery of thousands of loci for hundreds of phenotypes. However, the issue of missing heritability remains unsolved for most complex traits. Locus discovery could be enhanced with both improved power through multi-phenotype analysis (MPA) and u...

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Detalhes bibliográficos
Publicado no:Eur J Hum Genet
Main Authors: Kaakinen, Marika, Mägi, Reedik, Fischer, Krista, Heikkinen, Jani, Järvelin, Marjo-Riitta, Morris, Andrew P, Prokopenko, Inga
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513099/
https://ncbi.nlm.nih.gov/pubmed/28537275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2017.90
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