Human Neural Stem Cell Grafts Modify Microglial Response and Enhance Axonal Sprouting In Neonatal Hypoxic-Ischemic Brain Injury

BACKGROUND AND PURPOSE: Hypoxic-Ischemic (HI) brain injury in newborn infants represents a major cause of cerebral palsy, development delay and epilepsy. Stem cell-based therapy has the potential to rescue and replace the ischemic tissue caused by HI and to restore function. However, the mechanisms...

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Publicado no:Stroke
Main Authors: Daadi, Marcel M., Davis, Alexis, Arac, Ahmet, Li, Zongjin, Maag, Anne-Lise, Bhatnagar, Rishi, Jiang, Kewen, Sun, Guohua, Wu, Joseph C, Steinberg, Gary K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512869/
https://ncbi.nlm.nih.gov/pubmed/20075340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.109.573691
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