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Formation of platinum (II) as a six member ring for sustained polymeric delivery

A new pH-activated polymer chelate of cisplatin was synthesized using a scalable and green aqueous technique. Synthesis of the chelate was based on formation of a 6-member ring of platinum(II) with acetyl-homo-Lysine (Ac-homo-Lys), which was accomplished under completely aqueous conditions using a t...

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Détails bibliographiques
Publié dans:Eur J Med Chem
Auteurs principaux: Senadheera, Sanjeewa N., Zhang, Ti, Groer, Chad E., Forrest, M. Laird
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512711/
https://ncbi.nlm.nih.gov/pubmed/28525843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2017.05.020
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