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Sex bias in CNS autoimmune disease mediated by androgen control of autoimmune regulator

Male gender is protective against multiple sclerosis and other T-cell-mediated autoimmune diseases. This protection may be due, in part, to higher androgen levels in males. Androgen binds to the androgen receptor (AR) to regulate gene expression, but how androgen protects against autoimmunity is not...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Zhu, Meng-Lei, Bakhru, Pearl, Conley, Bridget, Nelson, Jennifer S., Free, Meghan, Martin, Aaron, Starmer, Joshua, Wilson, Elizabeth M., Su, Maureen A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512610/
https://ncbi.nlm.nih.gov/pubmed/27072778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11350
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