An Open-Label, Randomized, Parallel, Phase III Trial Evaluating the Efficacy and Safety of Polymeric Micelle-Formulated Paclitaxel Compared to Conventional Cremophor EL-Based Paclitaxel for Recurrent or Metastatic HER2-Negative Breast Cancer

PURPOSE: Genexol-PM is a Cremophor EL–free formulation of low-molecular-weight, non-toxic, and biodegradable polymeric micelle-bound paclitaxel. We conducted a phase III study comparing the clinical efficacy and toxicity of Genexol-PM with conventional paclitaxel (Genexol). MATERIALS AND METHODS: Pa...

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Publicado en:Cancer Res Treat
Autores principales: Park, In Hae, Sohn, Joo Hyuk, Kim, Sung Bae, Lee, Keun Seok, Chung, Joo Seop, Lee, Soo Hyeon, Kim, Tae You, Jung, Kyung Hae, Cho, Eun Kyung, Kim, Yang Soo, Song, Hong Suk, Seo, Jae Hong, Ryoo, Hun Mo, Lee, Sun Ah, Yoon, So Young, Kim, Chul Soo, Kim, Yong Tai, Kim, Si Young, Jin, Mi Ryung, Ro, Jungsil
Formato: Artigo
Lenguaje:Inglês
Publicado: Korean Cancer Association 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512366/
https://ncbi.nlm.nih.gov/pubmed/27618821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2016.289
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