An Open-Label, Randomized, Parallel, Phase III Trial Evaluating the Efficacy and Safety of Polymeric Micelle-Formulated Paclitaxel Compared to Conventional Cremophor EL-Based Paclitaxel for Recurrent or Metastatic HER2-Negative Breast Cancer

PURPOSE: Genexol-PM is a Cremophor EL–free formulation of low-molecular-weight, non-toxic, and biodegradable polymeric micelle-bound paclitaxel. We conducted a phase III study comparing the clinical efficacy and toxicity of Genexol-PM with conventional paclitaxel (Genexol). MATERIALS AND METHODS: Pa...

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書誌詳細
出版年:Cancer Res Treat
主要な著者: Park, In Hae, Sohn, Joo Hyuk, Kim, Sung Bae, Lee, Keun Seok, Chung, Joo Seop, Lee, Soo Hyeon, Kim, Tae You, Jung, Kyung Hae, Cho, Eun Kyung, Kim, Yang Soo, Song, Hong Suk, Seo, Jae Hong, Ryoo, Hun Mo, Lee, Sun Ah, Yoon, So Young, Kim, Chul Soo, Kim, Yong Tai, Kim, Si Young, Jin, Mi Ryung, Ro, Jungsil
フォーマット: Artigo
言語:Inglês
出版事項: Korean Cancer Association 2017
主題:
Original Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512366/
https://ncbi.nlm.nih.gov/pubmed/27618821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2016.289
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