An Open-Label, Randomized, Parallel, Phase III Trial Evaluating the Efficacy and Safety of Polymeric Micelle-Formulated Paclitaxel Compared to Conventional Cremophor EL-Based Paclitaxel for Recurrent or Metastatic HER2-Negative Breast Cancer

PURPOSE: Genexol-PM is a Cremophor EL–free formulation of low-molecular-weight, non-toxic, and biodegradable polymeric micelle-bound paclitaxel. We conducted a phase III study comparing the clinical efficacy and toxicity of Genexol-PM with conventional paclitaxel (Genexol). MATERIALS AND METHODS: Pa...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Res Treat
Prif Awduron: Park, In Hae, Sohn, Joo Hyuk, Kim, Sung Bae, Lee, Keun Seok, Chung, Joo Seop, Lee, Soo Hyeon, Kim, Tae You, Jung, Kyung Hae, Cho, Eun Kyung, Kim, Yang Soo, Song, Hong Suk, Seo, Jae Hong, Ryoo, Hun Mo, Lee, Sun Ah, Yoon, So Young, Kim, Chul Soo, Kim, Yong Tai, Kim, Si Young, Jin, Mi Ryung, Ro, Jungsil
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Korean Cancer Association 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512366/
https://ncbi.nlm.nih.gov/pubmed/27618821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2016.289
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