HIV-1 Infection Primes Macrophages Through STAT Signaling to Promote Enhanced Inflammation and Viral Replication

Macrophages play important roles in HIV-1 pathogenesis as targets for viral replication and mediators of chronic inflammation. Similar to IFNγ-priming, HIV-1 primes macrophages, resulting in hyperresponsiveness to subsequent toll-like receptor (TLR) stimulation and increased inflammatory cytokine pr...

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Enregistré dans:
Détails bibliographiques
Publié dans:AIDS Res Hum Retroviruses
Auteurs principaux: Appelberg, K. Sofia, Wallet, Mark A., Taylor, Jared P., Cash, Melanie N., Sleasman, John W., Goodenow, Maureen M.
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2017
Sujets:
Pathogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512335/
https://ncbi.nlm.nih.gov/pubmed/28142265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2016.0273
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