A Point Mutation in the Rhesus Rotavirus VP4 Protein Generated through a Rotavirus Reverse Genetics System Attenuates Biliary Atresia in the Murine Model

Rotavirus infection is one of the most common causes of diarrheal illness in humans. In neonatal mice, rhesus rotavirus (RRV) can induce biliary atresia (BA), a disease resulting in inflammatory obstruction of the extrahepatic biliary tract and intrahepatic bile ducts. We previously showed that the...

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Vydáno v:J Virol
Hlavní autoři: Mohanty, Sujit K., Donnelly, Bryan, Dupree, Phylicia, Lobeck, Inna, Mowery, Sarah, Meller, Jaroslaw, McNeal, Monica, Tiao, Greg
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512261/
https://ncbi.nlm.nih.gov/pubmed/28515290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00510-17
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