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A Point Mutation in the Rhesus Rotavirus VP4 Protein Generated through a Rotavirus Reverse Genetics System Attenuates Biliary Atresia in the Murine Model

Rotavirus infection is one of the most common causes of diarrheal illness in humans. In neonatal mice, rhesus rotavirus (RRV) can induce biliary atresia (BA), a disease resulting in inflammatory obstruction of the extrahepatic biliary tract and intrahepatic bile ducts. We previously showed that the...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Mohanty, Sujit K., Donnelly, Bryan, Dupree, Phylicia, Lobeck, Inna, Mowery, Sarah, Meller, Jaroslaw, McNeal, Monica, Tiao, Greg
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512261/
https://ncbi.nlm.nih.gov/pubmed/28515290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00510-17
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