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A Click Chemistry Approach to Identify Protein Targets of Cancer Chemopreventive Phenethyl Isothiocyanate

Here we report the identification of protein targets of chemopreventive phenethyl isothiocyanate (PEITC) via “click” chemistry in the A549 human lung cancer cell line, using a novel alkyne-tagged PEITC which was also found to show potent in vitro anticancer activity.

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Detalhes bibliográficos
Publicado no:RSC Adv
Main Authors: Fu, Ying, Mi, Lixin, Sanda, Miloslav, Silverstein, Shana, Aggarwal, Monika, Wang, Deyun, Gupta, Pankaj, Goldman, Radoslav, Appella, Daniel H., Chung, Fung-Lung
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512166/
https://ncbi.nlm.nih.gov/pubmed/28725420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3RA46849F
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