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A Click Chemistry Approach to Identify Protein Targets of Cancer Chemopreventive Phenethyl Isothiocyanate

Here we report the identification of protein targets of chemopreventive phenethyl isothiocyanate (PEITC) via “click” chemistry in the A549 human lung cancer cell line, using a novel alkyne-tagged PEITC which was also found to show potent in vitro anticancer activity.

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Detalles Bibliográficos
Publicado en:RSC Adv
Autores principales: Fu, Ying, Mi, Lixin, Sanda, Miloslav, Silverstein, Shana, Aggarwal, Monika, Wang, Deyun, Gupta, Pankaj, Goldman, Radoslav, Appella, Daniel H., Chung, Fung-Lung
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512166/
https://ncbi.nlm.nih.gov/pubmed/28725420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3RA46849F
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