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A Click Chemistry Approach to Identify Protein Targets of Cancer Chemopreventive Phenethyl Isothiocyanate

Here we report the identification of protein targets of chemopreventive phenethyl isothiocyanate (PEITC) via “click” chemistry in the A549 human lung cancer cell line, using a novel alkyne-tagged PEITC which was also found to show potent in vitro anticancer activity.

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Dades bibliogràfiques
Publicat a:RSC Adv
Autors principals: Fu, Ying, Mi, Lixin, Sanda, Miloslav, Silverstein, Shana, Aggarwal, Monika, Wang, Deyun, Gupta, Pankaj, Goldman, Radoslav, Appella, Daniel H., Chung, Fung-Lung
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512166/
https://ncbi.nlm.nih.gov/pubmed/28725420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3RA46849F
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