Synthetic aminopyrrolic receptors have apoptosis inducing activity

We report two synthetic aminopyrrolic compounds that induce apoptotic cell death. These compounds have been previously shown to act as receptors for mannosides. The extent of receptor-induced cell death is greater in cells expressing a high level of high-mannose oligosaccharides than in cells produc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chem Sci
Prif Awduron: Park, Seong-Hyun, Choi, Yoon Pyo, Park, Jinhong, Share, Andrew, Francesconi, Oscar, Nativi, Cristina, Namkung, Wan, Sessler, Jonathan L., Roelens, Stefano, Shin, Injae
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Royal Society of Chemistry 2015
Pynciau:
Chemistry
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512143/
https://ncbi.nlm.nih.gov/pubmed/28757987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03200h
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