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The sialate O-acetylesterase EstA from gut Bacteroidetes species enables sialidase-mediated cross-species foraging of 9-O-acetylated sialoglycans

The gut harbors many symbiotic, commensal, and pathogenic microbes that break down and metabolize host carbohydrates. Sialic acids are prominent outermost carbohydrates on host glycoproteins called mucins and protect underlying glycan chains from enzymatic degradation. Sialidases produced by some me...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Robinson, Lloyd S., Lewis, Warren G., Lewis, Amanda L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512079/
https://ncbi.nlm.nih.gov/pubmed/28526748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.769232
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