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The sialate O-acetylesterase EstA from gut Bacteroidetes species enables sialidase-mediated cross-species foraging of 9-O-acetylated sialoglycans

The gut harbors many symbiotic, commensal, and pathogenic microbes that break down and metabolize host carbohydrates. Sialic acids are prominent outermost carbohydrates on host glycoproteins called mucins and protect underlying glycan chains from enzymatic degradation. Sialidases produced by some me...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Robinson, Lloyd S., Lewis, Warren G., Lewis, Amanda L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512079/
https://ncbi.nlm.nih.gov/pubmed/28526748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.769232
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