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Cl(−) channel is required for CXCL10-induced neuronal activation and itch response in a murine model of allergic contact dermatitis

Persistent itch often accompanies allergic contact dermatitis (ACD), but the underlying mechanisms remain largely unexplored. We previously demonstrated that CXCL10/CXCR3 signaling activated a subpopulation of cutaneous primary sensory neurons and mediated itch response after contact hypersensitivit...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Qu, Lintao, Fu, Kai, Shimada, Steven G., LaMotte, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511864/
https://ncbi.nlm.nih.gov/pubmed/28446581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00187.2017
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