CXCR3 chemokine receptor signaling mediates itch in experimental allergic contact dermatitis

Persistent itch is a common symptom of allergic contact dermatitis (ACD) and represents a significant health burden. The chemokine CXCL10 is predominantly produced by epithelial cells during ACD. Although the chemokine CXCL10 and its receptor CXCR3 are implicated in the pathophysiology of ACD, it is...

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Veröffentlicht in:Pain
Hauptverfasser: Qu, Lintao, Fu, Kai, Yang, Jennifer, Shimada, Steven G., LaMotte, Robert H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545682/
https://ncbi.nlm.nih.gov/pubmed/25932692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000000208
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