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FFA3 activation stimulates duodenal bicarbonate secretion and prevents NSAID-induced enteropathy via the GLP-2 pathway in rats

Therapy with nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with enteropathy in humans and experimental animals, a cause of considerable morbidity. Unlike foregut NSAID-associated mucosal lesions, most treatments for this condition are of little efficacy. We propose that the endogenousl...

詳細記述

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書誌詳細
出版年:Dig Dis Sci
主要な著者: Said, Hyder, Akiba, Yasutada, Narimatsu, Kazuyuki, Maruta, Koji, Kuri, Ayaka, Iwamoto, Ken-ichi, Kuwahara, Atsukazu, Kaunitz, Jonathan D.
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511769/
https://ncbi.nlm.nih.gov/pubmed/28523577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-017-4600-4
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