Automated Image Analysis of HER2 Fluorescence In Situ Hybridization to Refine Definitions of Genetic Heterogeneity in Breast Cancer Tissue

Human epidermal growth factor receptor 2 gene- (HER2-) targeted therapy for breast cancer relies primarily on HER2 overexpression established by immunohistochemistry (IHC) with borderline cases being further tested for amplification by fluorescence in situ hybridization (FISH). Manual interpretation...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Radziuviene, Gedmante, Rasmusson, Allan, Augulis, Renaldas, Lesciute-Krilaviciene, Daiva, Laurinaviciene, Aida, Clim, Eduard, Laurinavicius, Arvydas
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511668/
https://ncbi.nlm.nih.gov/pubmed/28752092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2321916
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