Membrane connectivity estimated by digital image analysis of HER2 immunohistochemistry is concordant with visual scoring and fluorescence in situ hybridization results: algorithm evaluation on breast cancer tissue microarrays

INTRODUCTION: The human epidermal growth factor receptor 2 (HER2) is an established biomarker for management of patients with breast cancer. While conventional testing of HER2 protein expression is based on semi-quantitative visual scoring of the immunohistochemistry (IHC) result, efforts to reduce...

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Autori principali: Laurinaviciene, Aida, Dasevicius, Darius, Ostapenko, Valerijus, Jarmalaite, Sonata, Lazutka, Juozas, Laurinavicius, Arvydas
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Methodology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191356/
https://ncbi.nlm.nih.gov/pubmed/21943197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-6-87
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