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Exposure-Response Analysis of Alvocidib (Flavopiridol) Treatment by Bolus or Hybrid Administration in Newly Diagnosed or Relapsed/Refractory Acute Leukemia Patients
PURPOSE: To elucidate any differences in the exposure-response of alvocidib (flavopiridol) given by 1 hour bolus or a hybrid schedule (30 minute bolus followed by a 4 hour infusion) using a flavopiridol/cytosine arabinoside/mitoxantrone sequential protocol (FLAM) in acute leukemia patients. The hybr...
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| Publicado no: | Clin Cancer Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5511568/ https://ncbi.nlm.nih.gov/pubmed/28174232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2629 |
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