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Gleason Score 7 Prostate Cancers Emerge Through Branched Evolution of Clonal Gleason Pattern 3 and 4

PURPOSE: The molecular features that account for the distinct histology and aggressive biological behavior of Gleason pattern 4 (Gp4) versus Gp3 prostate cancer (PCa), and whether Gp3 tumors progress directly to Gp4, remain to be established. EXPERIMENTAL DESIGN: Whole exome sequencing and transcrip...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Sowalsky, Adam G., Kissick, Haydn T., Gerrin, Sean J., Schaefer, Rachel J., Xia, Zheng, Russo, Joshua W., Arredouani, M. Simo, Bubley, Glenn J., Sanda, Martin G., Li, Wei, Ye, Huihui, Balk, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511561/
https://ncbi.nlm.nih.gov/pubmed/28119368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2414
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