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Dietary geranylgeraniol can limit the activity of pitavastatin as a potential treatment for drug-resistant ovarian cancer

Pre-clinical and retrospective studies of patients using statins to reduce plasma cholesterol have suggested that statins may be useful to treat cancer. However, prospective clinical trials have yet to demonstrate significant efficacy. We have previously shown that this is in part because a hydropho...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: de Wolf, Elizabeth, Abdullah, Marwan Ibrahim, Jones, Stefanie M., Menezes, Karen, Moss, Darren M., Drijfhout, Falko P., Hart, Sarah R., Hoskins, Clare, Stronach, Euan A., Richardson, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511264/
https://ncbi.nlm.nih.gov/pubmed/28710496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05595-4
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