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TALEN based HPV-E7 editing triggers necrotic cell death in cervical cancer cells
Human Papillomavirus E7 and E6 oncoproteins have been considered as suitable candidate anti-viral targets since they cause malignant conversion in cervical cancers. Transcription Activator-Like Effector Nucleases (TALENs) are recent editing tools to knockout genes by inducing double stranded breaks...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5511212/ https://ncbi.nlm.nih.gov/pubmed/28710417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05696-0 |
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