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Brain specific Lamellipodin knockout results in hyperactivity and increased anxiety of mice
Lamellipodin (Lpd) functions as an important signalling integrator downstream of growth factor and axon guidance receptors. Mechanistically, Lpd promotes actin polymerization by interacting with F-actin and the actin effectors Ena/VASP proteins and the SCAR/WAVE complex. Thereby, Lpd supports lamell...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5511208/ https://ncbi.nlm.nih.gov/pubmed/28710397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05043-3 |
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