TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors

Understanding the processes that govern liver progenitor cell differentiation has important implications for the design of strategies targeting chronic liver diseases, whereby regeneration of liver tissue is critical. Although DNA methylation (5mC) and hydroxymethylation (5hmC) are highly dynamic du...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Ancey, Pierre-Benoit, Ecsedi, Szilvia, Lambert, Marie-Pierre, Talukdar, Fazlur Rahman, Cros, Marie-Pierre, Glaise, Denise, Narvaez, Diana Maria, Chauvet, Veronique, Herceg, Zdenko, Corlu, Anne, Hernandez-Vargas, Hector
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511103/
https://ncbi.nlm.nih.gov/pubmed/28648900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.05.023
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