TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors

Understanding the processes that govern liver progenitor cell differentiation has important implications for the design of strategies targeting chronic liver diseases, whereby regeneration of liver tissue is critical. Although DNA methylation (5mC) and hydroxymethylation (5hmC) are highly dynamic du...

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Publicat a:Stem Cell Reports
Autors principals: Ancey, Pierre-Benoit, Ecsedi, Szilvia, Lambert, Marie-Pierre, Talukdar, Fazlur Rahman, Cros, Marie-Pierre, Glaise, Denise, Narvaez, Diana Maria, Chauvet, Veronique, Herceg, Zdenko, Corlu, Anne, Hernandez-Vargas, Hector
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511103/
https://ncbi.nlm.nih.gov/pubmed/28648900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.05.023
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