The Developmental Stage of Adult Human Stem Cell-Derived Retinal Pigment Epithelium Cells Influences Transplant Efficacy for Vision Rescue

Age-related macular degeneration (AMD) is a common cause of central visual loss in the elderly. Retinal pigment epithelial (RPE) cell loss occurs early in the course of AMD and RPE cell transplantation holds promise to slow disease progression. We report that subretinal transplantation of RPE stem c...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Davis, Richard J., Alam, Nazia M., Zhao, Cuiping, Müller, Claudia, Saini, Janmeet S., Blenkinsop, Timothy A., Mazzoni, Francesca, Campbell, Melissa, Borden, Susan M., Charniga, Carol J., Lederman, Patty L., Aguilar, Vanessa, Naimark, Michael, Fiske, Michael, Boles, Nathan, Temple, Sally, Finnemann, Silvia C., Prusky, Glen T., Stern, Jeffrey H.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511099/
https://ncbi.nlm.nih.gov/pubmed/28625537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.05.016
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