The Developmental Stage of Adult Human Stem Cell-Derived Retinal Pigment Epithelium Cells Influences Transplant Efficacy for Vision Rescue

Age-related macular degeneration (AMD) is a common cause of central visual loss in the elderly. Retinal pigment epithelial (RPE) cell loss occurs early in the course of AMD and RPE cell transplantation holds promise to slow disease progression. We report that subretinal transplantation of RPE stem c...

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Publicado en:Stem Cell Reports
Autores principales: Davis, Richard J., Alam, Nazia M., Zhao, Cuiping, Müller, Claudia, Saini, Janmeet S., Blenkinsop, Timothy A., Mazzoni, Francesca, Campbell, Melissa, Borden, Susan M., Charniga, Carol J., Lederman, Patty L., Aguilar, Vanessa, Naimark, Michael, Fiske, Michael, Boles, Nathan, Temple, Sally, Finnemann, Silvia C., Prusky, Glen T., Stern, Jeffrey H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
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Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511099/
https://ncbi.nlm.nih.gov/pubmed/28625537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2017.05.016
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