Clearance of viable Mycobacterium ulcerans from Buruli ulcer lesions during antibiotic treatment as determined by combined 16S rRNA reverse transcriptase /IS 2404 qPCR assay

INTRODUCTION: Buruli ulcer (BU) caused by Mycobacterium ulcerans is effectively treated with rifampicin and streptomycin for 8 weeks but some lesions take several months to heal. We have shown previously that some slowly healing lesions contain mycolactone suggesting continuing infection after antib...

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Vydáno v:PLoS Negl Trop Dis
Hlavní autoři: Sarpong-Duah, Mabel, Frimpong, Michael, Beissner, Marcus, Saar, Malkin, Laing, Ken, Sarpong, Francisca, Loglo, Aloysius Dzigbordi, Abass, Kabiru Mohammed, Frempong, Margaret, Sarfo, Fred Stephen, Bretzel, Gisela, Wansbrough-Jones, Mark, Phillips, Richard Odame
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510892/
https://ncbi.nlm.nih.gov/pubmed/28671942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005695
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