Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis

BACKGROUND: Acute-serum Amyloid A (A-SAA), one of the major acute-phase proteins, is mainly produced in the liver but extra-hepatic synthesis involving the skin has been reported. Its expression is regulated by the transcription factors NF-κB, C/EBPβ, STAT3 activated by proinflammatory cytokines. OB...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Couderc, Elodie, Morel, Franck, Levillain, Pierre, Buffière-Morgado, Amandine, Camus, Magalie, Paquier, Camille, Bodet, Charles, Jégou, Jean-François, Pohin, Mathilde, Favot, Laure, Garcia, Martine, Huguier, Vincent, Mcheik, Jiad, Lacombe, Corinne, Yssel, Hans, Guillet, Gérard, Bernard, François-Xavier, Lecron, Jean-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510841/
https://ncbi.nlm.nih.gov/pubmed/28708859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181486
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